Therapy Detail
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| Therapy Name | YH001 + YH002 |
| Synonyms | |
| Therapy Description | |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| YH001 | YH 001|YH-001 | CTLA4 Antibody 33 | YH001 is a humanized anti-CTLA4 antibody that may block immunosuppression in tumor microenvironment and enhance antitumor immune response (J Clin Oncol 39, no. 15_suppl (May 20, 2021) 2577-2577). | |
| YH002 | YH 002|YH-002 | OX40 Antibody 15 | YH002 is a humanized agonist OX40 (CD134, TNFRSF4) antibody that activates OX40 downstream signaling, potentially leading to anti-tumor immune response (J Clin Oncol 39, no. 15_suppl, abstract e14501). |
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- Case insensitive filtering will display rows if any text in any cell matches the filter term
- Use simple literal full or partial string matches
- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
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- Click on any column header arrows to sort by that column
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
Filtering
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- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
- Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
Sorting
- Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
- Click on any column header arrows to sort by that column
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| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT05169697 | Phase I | YH001 + YH002 | A Study to Assess YH002 in Combination With YH001 in Subjects With Advanced Solid Tumors | Completed | AUS | 1 |
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