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Therapy Name | BGB-24714 |
Synonyms | |
Therapy Description |
BGB-24714 is a mimetic of second mitochondrial-derived activator of caspases (Smac), which inhibits the activities of inhibitor of apoptosis (IAP) proteins, potentially leading to apoptosis of tumor cells (NCI Drug Dictionary). |
Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
---|---|---|---|---|
BGB-24714 | BGB 24714|BGB24714 | BGB-24714 is a mimetic of second mitochondrial-derived activator of caspases (Smac), which inhibits the activities of inhibitor of apoptosis (IAP) proteins, potentially leading to apoptosis of tumor cells (NCI Drug Dictionary). |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
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Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
---|---|---|---|---|---|---|
NCT05381909 | Phase I | BGB-24714 + Paclitaxel BGB-24714 | Study Investigating BGB-24714 as Monotherapy and in Combination With Chemotherapy in Participants With Advanced or Metastatic Solid Tumors | Recruiting | USA | NZL | AUS | 2 |