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Therapy Name IBI363
Synonyms
Therapy Description

IBI363 is a bispecific antibody fusion protein comprised of a monoclonal antibody that targets PD-1 (PDCD1) linked to a modified form of IL-2, which potentially leads to decreased PD-1 signaling, elevated IL-2-dependent signaling, and restoration of the anti-tumor immune response (NCI Drug Dictionary).

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Drug Name Trade Name Synonyms Drug Classes Drug Description
IBI363 IBI-363|IBI 363 PD-L1/PD-1 antibody 121 IBI363 is a bispecific antibody fusion protein comprised of a monoclonal antibody that targets PD-1 (PDCD1) linked to a modified form of IL-2, which potentially leads to decreased PD-1 signaling, elevated IL-2-dependent signaling, and restoration of the anti-tumor immune response (NCI Drug Dictionary).

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT06281678 Phase II IBI363 A Study of IBI363 in Subjects With Advanced Solid Malignancies Recruiting USA 0
NCT05290597 Phase I IBI363 A Phase 1, Open-label, Multicenter, Dose Escalation Study of IBI363 (PD1-IL2m) in Subjects With Advanced Solid Malignancies or Lymphomas Unknown status AUS 0


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