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Therapy Name IMP9064
Synonyms
Therapy Description

IMP9064 binds to and inhibits ATR, resulting in inhibition of downstream signaling and impaired DNA damage repair, potentially leading to induction of apoptosis in tumor cells and antitumor activity (NCI Drug Dictionary, Ann Oncol 34 (2023): S476-S477).

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Drug Name Trade Name Synonyms Drug Classes Drug Description
IMP9064 IMP-9064|IMP 9064 ATR Inhibitor 16 IMP9064 binds to and inhibits ATR, resulting in inhibition of downstream signaling and impaired DNA damage repair, potentially leading to induction of apoptosis in tumor cells and antitumor activity (NCI Drug Dictionary, Ann Oncol 34 (2023): S476-S477).

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT05269316 Phase I IMP9064 Study to Evaluate IMP9064 as a Monotherapy or in Combination in Patients With Advanced Solid Tumors Recruiting USA | AUS 2


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