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Therapy Detail
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| Therapy Name | ARI-0001 |
| Synonyms | |
| Therapy Description |
ARI-0001 are autologous T-lymphocytes engineered to express a CD137-based chimeric antigen receptor (CAR) targeting CD19, which may have antitumor activity (PMID: 35174095). |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| ARI-0001 | ARI0001|ARI 0001|PEI 19-187 | CD19 Immune Cell Therapy 65 | ARI-0001 are autologous T-lymphocytes engineered to express a CD137-based chimeric antigen receptor (CAR) targeting CD19, which may have antitumor activity (PMID: 35174095). |
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
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| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT04778579 | Phase II | ARI-0001 | Study of the Infusion of ARI-0001 Cells in Patients With CD19 + Acute Lymphoid Leukemia Resistant or Refractory to Therapy (CART19-BE-02) | Active, not recruiting | ESP | 0 |
| NCT05641428 | Phase II | axicabtagene ciloleucel ARI-0001 | Comparison of Point-of-care Produced CAR T-cell With Commercial CAR T-cells in Patients With R/R LBCL (HOVON161) | Recruiting | NLD | 0 |
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