Therapy Detail
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| Therapy Name | ARX517 |
| Synonyms | |
| Therapy Description |
ARX517 is an antibody-drug conjugate (ADC) comprising a monoclonal antibody against PSMA linked to pAF-AS269, which targets the anti-microtubule agent to PSMA-expressing cells, potentially inhibiting growth of PSMA-positive tumor cells (PMID: 39172730). |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| ARX517 | ARX 517|ARX-517|JNJ-95298177|JNJ95298177|JNJ95298177 | PSMA Antibody 23 | ARX517 is an antibody-drug conjugate (ADC) comprising a monoclonal antibody against PSMA linked to pAF-AS269, which targets the anti-microtubule agent to PSMA-expressing cells, potentially inhibiting growth of PSMA-positive tumor cells (PMID: 39172730). |
Filtering
- Case insensitive filtering will display rows if any text in any cell matches the filter term
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- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
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- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
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- Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
- Click on any column header arrows to sort by that column
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| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT04662580 | Phase I | ARX517 | ARX517 in Subjects With Advanced Solid Tumor (ARX517) | Recruiting | USA | 0 |
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