Therapy Detail
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| Therapy Name | Divarasib + GDC-1971 |
| Synonyms | |
| Therapy Description | |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| Divarasib | GDC-6036|GDC6036|GDC 6036 | KRAS G12C inhibitor 34 | Divarasib (GDC-6036) is a selective inhibitor of KRAS G12C that blocks downstream signaling, and may lead to anti-tumor activity (PMID: 37611121). | |
| GDC-1971 | RLY1971|RLY 1971|RG-6433|RG6433|RLY-1971|GDC1971|GDC 1971 | SHP2 Inhibitor 20 | RLY-1971 is a selective SHP2 inhibitor, which potentially decreases tumor growth (PMID: 37774359). |
Filtering
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
Filtering
- Case insensitive filtering will display rows if any text in any cell matches the filter term
- Use simple literal full or partial string matches
- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
- Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
Sorting
- Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
- Click on any column header arrows to sort by that column
- Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.
| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|
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