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Therapy Name Aldesleukin + AU-007
Synonyms
Therapy Description

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Drug Name Trade Name Synonyms Drug Classes Drug Description
AU-007 AU 007|AU007 AU-007 is an antibody that binds to IL-2 and prevents binding to CD25, potentially leading to activation of immune effector cells, decreased expansion of T-regulatory cells, and inhibition of tumor growth (Journal for ImmunoTherapy of Cancer 2021;9).
Aldesleukin Proleukin IL-2|Interleukin-2|IL2 Aldesleukin (IL-2) is a cytokine that potentially modulates antitumor immune response (NCI Drug Dictionary).

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT05267626 Phase Ib/II Aldesleukin + AU-007 + Nivolumab Aldesleukin + AU-007 + Avelumab Aldesleukin + AU-007 AU-007 Study of AU-007, A Monoclonal Antibody That Binds to IL-2 and Inhibits IL-2Ralpha Binding, in Patients With Unresectable Locally Advanced or Metastatic Cancer Recruiting USA | AUS 0


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