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Therapy Name | DS-9606a |
Synonyms | |
Therapy Description |
DS-9606a is an antibody-drug conjugate (ADC) composed of a monoclonal antibody targeting CLDN6 linked to the cytotoxic agent pyrrolobenzodiazepine, which potentially induces killing of CLDN6-expressing tumor cells (Ann Oncol (2024) 35 (Suppl_2): S488 - S489, NCI Drug Dictionary). |
Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
---|---|---|---|---|
DS-9606a | DS9606a|DS 9606a|DS9606|DS 9606|DS-9606 | CLDN6 Antibody 8 | DS-9606a is an antibody-drug conjugate (ADC) composed of a monoclonal antibody targeting CLDN6 linked to the cytotoxic agent pyrrolobenzodiazepine, which potentially induces killing of CLDN6-expressing tumor cells (Ann Oncol (2024) 35 (Suppl_2): S488 - S489, NCI Drug Dictionary). |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
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Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
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NCT05394675 | Phase I | DS-9606a | A Study of DS-9606a in Patients With Advanced Solid Tumors | Recruiting | USA | GBR | 0 |