Therapy Detail
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| Therapy Name | HB0025 |
| Synonyms | |
| Therapy Description |
HB0025 is a bispecific antibody comprised of a monoclonal antibody targeting CD274 (PD-L1) fused to extracellular domain 2 of VEGFR1 to target VEGF, which potentially inhibits tumor growth (PMID: 34925354). |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| HB0025 | HB-0025|HB 0025 | PD-L1/PD-1 antibody 131 VEGF Antibody 13 | HB0025 is a bispecific antibody comprised of a monoclonal antibody targeting CD274 (PD-L1) fused to extracellular domain 2 of VEGFR1 to target VEGF, which potentially inhibits tumor growth (PMID: 34925354). |
Filtering
- Case insensitive filtering will display rows if any text in any cell matches the filter term
- Use simple literal full or partial string matches
- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
- Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
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- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
- Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
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- Click on any column header arrows to sort by that column
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| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT04678908 | Phase I | HB0025 | A Study of Injection HB0025 in Patients With Advanced Solid Tumors | Unknown status | USA | 1 |
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