Therapy Detail
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| Therapy Name | TK-8001 |
| Synonyms | |
| Therapy Description |
TK-8001 is a T-cell receptor-based therapy that targets melanoma-associated antigen 1 (MAGE-A1) expressed on tumor cells, potentially resulting in antitumor activity (Journal for ImmunoTherapy of Cancer 2021;9). |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| TK-8001 | TK 8001|TK8001 | TK-8001 is a T-cell receptor-based therapy that targets melanoma-associated antigen 1 (MAGE-A1) expressed on tumor cells, potentially resulting in antitumor activity (Journal for ImmunoTherapy of Cancer 2021;9). |
Filtering
- Case insensitive filtering will display rows if any text in any cell matches the filter term
- Use simple literal full or partial string matches
- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
- Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
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- Click on any column header arrows to sort by that column
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
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- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
- Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
Sorting
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- Click on any column header arrows to sort by that column
- Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.
| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT05430555 | Phase Ib/II | TK-8001 | A Phase 1/2, First-in-Human, Open-Label, Accelerated-Titration, Two-Part Clinical Trial of TK-8001 in Patients With HLA-A*02:01 Genotype and Advanced-Stage/Metastatic MAGE-A1+ Solid Tumors (IMAG1NE) | Terminated | NLD | GBR | ESP | DEU | BEL | 0 |
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