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Therapy Name | SGN-PDL1V |
Synonyms | |
Therapy Description |
SGN-PDL1V is an antibody-drug conjugate (ADC) comprised of a monoclonal antibody targeting CD274 (PD-L1) linked to monomethyl auristatin E (MMAE), which potentially induces cytotoxicity, immune activation, and inhibition of tumor growth (J of Clin Oncol 40, no. 16_suppl (June 01, 2022) TPS3154). |
Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
---|---|---|---|---|
SGN-PDL1V | SGNPDL1V|SGN PDL1V | PD-L1/PD-1 antibody 121 | SGN-PDL1V is an antibody-drug conjugate (ADC) comprised of a monoclonal antibody targeting CD274 (PD-L1) linked to monomethyl auristatin E (MMAE), which potentially induces cytotoxicity, immune activation, and inhibition of tumor growth (J of Clin Oncol 40, no. 16_suppl (June 01, 2022) TPS3154). |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
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Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
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NCT05208762 | Phase I | SGN-PDL1V | A Study of SGN-PDL1V in Advanced Solid Tumors | Recruiting | USA | NLD | ITA | GBR | FRA | ESP | DEU | CAN | BEL | 0 |