Therapy Detail
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| Therapy Name | Autologous TGF beta resistant HER2 EBV CTLs |
| Synonyms | |
| Therapy Description |
Autologous TGF beta resistant HER2 EBV CTLs are EBV-specific autologous cytotoxic T lymphocytes that express a chimeric ERBB2 (HER2) antigen receptor as well as a dominant negative TGF-beta receptor, which target ERBB2 (HER2) expressing tumor cells, potentially resulting in increased CTL-mediated tumor cell death (NCI Drug Dictionary). |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| Autologous TGF beta resistant HER2 EBV CTLs | HER2 (ERBB2) Immune Cell Therapy 9 | Autologous TGF beta resistant HER2 EBV CTLs are EBV-specific autologous cytotoxic T lymphocytes that express a chimeric ERBB2 (HER2) antigen receptor as well as a dominant negative TGF-beta receptor, which target ERBB2 (HER2) expressing tumor cells, potentially resulting in increased CTL-mediated tumor cell death (NCI Drug Dictionary). |
Filtering
- Case insensitive filtering will display rows if any text in any cell matches the filter term
- Use simple literal full or partial string matches
- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
- Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
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- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
- Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
Sorting
- Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
- Click on any column header arrows to sort by that column
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| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT00889954 | Phase I | Autologous TGF beta resistant HER2 EBV CTLs | Her2 and TGFBeta CTLs in Treatment of Her2 Positive Malignancy | Completed | USA | 0 |
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