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Therapy Name ORM-5029
Synonyms
Therapy Description

ORM-5029 is an antibody neodegrader conjugate comprising a GSPT1 degrader linked to pertuzumab, which may lead to growth inhibition of ERBB2 (HER2)-positive tumor cells, and decreased tumor growth (Cancer Res 2022;82(12_Suppl):Abstract nr 3933).

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Drug Name Trade Name Synonyms Drug Classes Drug Description
ORM-5029 ORM 5029|ORM5029 ORM-5029 is an antibody neodegrader conjugate comprising a GSPT1 degrader linked to pertuzumab, which may lead to growth inhibition of ERBB2 (HER2)-positive tumor cells, and decreased tumor growth (Cancer Res 2022;82(12_Suppl):Abstract nr 3933).

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  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References

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  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT05511844 Phase I ORM-5029 Study of ORM-5029 in Subjects With HER2-Expressing Advanced Solid Tumors Recruiting USA 0


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