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Therapy Name SGN-B7H4V
Synonyms
Therapy Description

SGN-B7H4V is an antibody-drug conjugate (ADC) comprised of a monoclonal antibody targeting VTCN1 (B7-H4) linked to monomethyl auristatin E (MMAE), which potentially induces cytotoxicity, phagocytosis, and tumor growth inhibition (Cancer Res 2022;82(12_Suppl):Abstract nr 1281).

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Drug Name Trade Name Synonyms Drug Classes Drug Description
SGN-B7H4V SGN B7H4V|SGNB7H4V SGN-B7H4V is an antibody-drug conjugate (ADC) comprised of a monoclonal antibody targeting VTCN1 (B7-H4) linked to monomethyl auristatin E (MMAE), which potentially induces cytotoxicity, phagocytosis, and tumor growth inhibition (Cancer Res 2022;82(12_Suppl):Abstract nr 1281).

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT05194072 Phase I SGN-B7H4V A Study of SGN-B7H4V in Advanced Solid Tumors Recruiting USA | ITA | GBR | ESP | DEU | CAN 0


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