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Therapy Name WU-CART-007
Synonyms
Therapy Description

WU-CART-007 are allogeneic T-lymphocytes that have been engineered to express a chimeric antigen receptor (CAR) that targets CD7, potentially resulting in killing of tumor cells expressing CD7 and inhibition of tumor growth (Blood (2021) 138 (Supplement 1): 2772).

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Drug Name Trade Name Synonyms Drug Classes Drug Description
WU-CART-007 WU-CART 007|WU-CART007 CD7 Immune Cell Therapy 4 WU-CART-007 are allogeneic T-lymphocytes that have been engineered to express a chimeric antigen receptor (CAR) that targets CD7, potentially resulting in killing of tumor cells expressing CD7 and inhibition of tumor growth (Blood (2021) 138 (Supplement 1): 2772).

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT05377827 Phase I WU-CART-007 Dose-Escalation and Dose-Expansion Study to Evaluate the Safety and Tolerability of Anti-CD7 Allogeneic CAR T-Cells (WU-CART-007) in Patients With CD7+ Hematologic Malignancies Active, not recruiting USA 0
NCT04984356 Phase Ib/II WU-CART-007 A Phase 1/2 Study of the Safety and Efficacy of Anti-CD7 Allogeneic CAR-T Cells (WU-CART-007) in Patients With Relapsed or Refractory T-ALL/LBL Completed USA | NLD | FRA | AUS 0
NCT06514794 Phase II WU-CART-007 A Phase 2 Study of WU-CART-007, an Anti-CD7 Allogeneic CAR-T Cell Therapy in T-Cell Acute Lymphoblastic Leukemia and Lymphoblastic Lymphoma (T-RRex) Recruiting USA | AUS 0


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