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Therapy Name BAY 3375968
Synonyms
Therapy Description

BAY 3375968 is an anti-CCR8 monoclonal antibody, which potentially reduces CCR8-positive regulatory T-cells in the tumor microenvironment through antibody dependent cellular cytotoxicity (ADCC) and cellular phagocytosis (ADCP) (Cancer Res 2022;82(12_Suppl):Abstract nr 2866).

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Drug Name Trade Name Synonyms Drug Classes Drug Description
BAY 3375968 BAY3375968|BAY-3375968 CCR8 Antibody 9 BAY 3375968 is an anti-CCR8 monoclonal antibody, which potentially reduces CCR8-positive regulatory T-cells in the tumor microenvironment through antibody dependent cellular cytotoxicity (ADCC) and cellular phagocytosis (ADCP) (Cancer Res 2022;82(12_Suppl):Abstract nr 2866).

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT05537740 Phase I BAY 3375968 + Pembrolizumab BAY 3375968 A First-in-human Study to Learn How Safe the Study Drug BAY3375968, an Anti-CCR8 Antibody, is, When Given Alone or in Combination With Pembrolizumab, How it Affects the Body, How it Moves Into, Through, and Out of the Body, and to Find the Best Dose in Participants With Advanced Solid Tumors Recruiting USA | GBR | FRA | ESP | CAN | BEL 2


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