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Therapy Name | S-531011 |
Synonyms | |
Therapy Description |
S-531011 is an antibody that targets CCR8, potentially resulting in antibody-dependent cellular cytotoxicity against regulatory T-cells expressing CCR8 and inhibition of tumor growth (Journal for ImmunoTherapy of Cancer 2021;9). |
Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
---|---|---|---|---|
S-531011 | S 531011|S531011 | CCR8 Antibody 9 | S-531011 is an antibody that targets CCR8, potentially resulting in antibody-dependent cellular cytotoxicity against regulatory T-cells expressing CCR8 and inhibition of tumor growth (Journal for ImmunoTherapy of Cancer 2021;9). |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
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Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
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NCT05101070 | Phase Ib/II | Pembrolizumab + S-531011 Pembrolizumab S-531011 | S-531011 as Monotherapy and in Combination With an Immune Checkpoint Inhibitor in Advanced or Metastatic Solid Tumors (aCCeleR8-001) | Recruiting | USA | 1 |