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Therapy Name MVR-C5252
Synonyms
Therapy Description

MVR-C5252 is a oncolytic herpes simplex virus type 1 modified to express IL-12 and an antibody targeting PDCD1 (PD-1), which potentially activates an anti-tumor immune response (NCI Drug Dictionary).

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Drug Name Trade Name Synonyms Drug Classes Drug Description
MVR-C5252 MVR C5252|MVRC5252|C5252|C-5252|C 5252 PD-L1/PD-1 antibody 121 MVR-C5252 is a oncolytic herpes simplex virus type 1 modified to express IL-12 and an antibody targeting PDCD1 (PD-1), which potentially activates an anti-tumor immune response (NCI Drug Dictionary).

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT05095441 Phase I MVR-C5252 A Clinical Study of Intratumoral MVR-C5252 (C5252) in Patients With Recurrent or Progressive Glioblastoma Not yet recruiting USA 0
NCT06126744 Phase I MVR-C5252 Open-Label Study to Evaluate the Safety, Tolerability and Efficacy of the Oncolytic HSV1 MVR-C5252 (PuMP) Recruiting USA 0


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