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Therapy Name YH32367
Synonyms
Therapy Description

YH32367 (ABL105) is a bispectific antibody targeting ERBB2 (HER2) and TNFRSF9 (4-1BB), which potentially enhances antitumor immune response and inhibits tumor growth (Cancer Res 2022;82(12_Suppl):Abstract nr 1139).

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Drug Name Trade Name Synonyms Drug Classes Drug Description
YH32367 YH 32367|YH-32367|ABL105|AB L105|AB-L105 HER2 (ERBB2) Antibody 76 TNFRSF9 Antibody 32 YH32367 (ABL105) is a bispectific antibody targeting ERBB2 (HER2) and TNFRSF9 (4-1BB), which potentially enhances antitumor immune response and inhibits tumor growth (Cancer Res 2022;82(12_Suppl):Abstract nr 1139).

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT05523947 Phase Ib/II YH32367 Clinical Trial of YH32367 in Patients With HER2 Positive Locally Advanced or Metastatic Solid Tumor Recruiting AUS 1


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