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Therapy Name INCA32459
Synonyms
Therapy Description

INCA32459 is a bispecific antibody that targets both PD-1 (PDCD1) and LAG3, potentially leading to increased antitumor immune response and inhibition of tumor growth (Journal for ImmunoTherapy of Cancer 2022;10).

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Drug Name Trade Name Synonyms Drug Classes Drug Description
INCA32459 INCA 32459|INCA-32459 LAG3 Antibody 18 PD-L1/PD-1 antibody 121 INCA32459 is a bispecific antibody that targets both PD-1 (PDCD1) and LAG3, potentially leading to increased antitumor immune response and inhibition of tumor growth (Journal for ImmunoTherapy of Cancer 2022;10).

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  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References

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  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
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Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT05577182 Phase I INCA32459 Study of INCA32459 a LAG-3 and PD-1 Bispecific Antibody in Participants With Select Advanced Malignancies Active, not recruiting USA | ITA | ESP | BEL 0


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