Therapy Detail
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| Therapy Name | INCA32459 |
| Synonyms | |
| Therapy Description |
INCA32459 is a bispecific antibody that targets both PD-1 (PDCD1) and LAG3, potentially leading to increased antitumor immune response and inhibition of tumor growth (Journal for ImmunoTherapy of Cancer 2022;10). |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| INCA32459 | INCA 32459|INCA-32459 | LAG3 Antibody 19 PD-L1/PD-1 antibody 132 | INCA32459 is a bispecific antibody that targets both PD-1 (PDCD1) and LAG3, potentially leading to increased antitumor immune response and inhibition of tumor growth (Journal for ImmunoTherapy of Cancer 2022;10). |
Filtering
- Case insensitive filtering will display rows if any text in any cell matches the filter term
- Use simple literal full or partial string matches
- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
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- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
- Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
Sorting
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- Click on any column header arrows to sort by that column
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| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT05577182 | Phase I | INCA32459 | Study of INCA32459 a LAG-3 and PD-1 Bispecific Antibody in Participants With Select Advanced Malignancies | Completed | USA | ITA | ESP | BEL | 0 |
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