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Therapy Name JK08
Synonyms
Therapy Description

JK08 comprises an anti-CTLA4 antibody fused to the IL-15/IL15Ralpha complex, which may result in T-cell activation and an increased anti-tumor immune response (Ann Oncol (2023) 34 (suppl_2): S635, Journal for ImmunoTherapy of Cancer 2023;11).

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Drug Name Trade Name Synonyms Drug Classes Drug Description
JK08 JK-08|JK 08 CTLA4 Antibody 31 JK08 comprises an anti-CTLA4 antibody fused to the IL-15/IL15Ralpha complex, which may result in T-cell activation and an increased anti-tumor immune response (Ann Oncol (2023) 34 (suppl_2): S635, Journal for ImmunoTherapy of Cancer 2023;11).

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT05620134 Phase Ib/II JK08 A Study of JK08, an IL-15 Antibody Fusion Protein Targeting CTLA-4, in Patients With Unresectable Locally Advanced or Metastatic Cancer Active, not recruiting ESP | BEL 0


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