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Therapy Name BDTX-1535
Synonyms
Therapy Description

BDTX-1535 is an irreversible fourth-generation EGFR inhibitor with activity against EGFR mutations, including mutations associated with resistance to third-generation inhibitors, which potentially reduces tumor growth (Eur J Cancer Vol 174, Supp 1:S14; Eur J Cancer, Vol 174, Supp 1:S22).

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Drug Name Trade Name Synonyms Drug Classes Drug Description
BDTX-1535 BDTX1535|BDTX 1535 EGFR Inhibitor 4th gen 16 BDTX-1535 is an irreversible fourth-generation EGFR inhibitor with activity against EGFR mutations, including mutations associated with resistance to third-generation inhibitors, which potentially reduces tumor growth (Eur J Cancer Vol 174, Supp 1:S14; Eur J Cancer, Vol 174, Supp 1:S22).

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  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT05256290 Phase I BDTX-1535 BDTX-1535 + Temozolomide Phase 1/2 Study of BDTX-1535 in Patients With Glioblastoma or Non-Small Cell Lung Cancer With EGFR Mutations Recruiting USA 0
NCT06072586 Phase I BDTX-1535 Study of BDTX-1535 in Recurrent High-Grade Glioma (HGG) Participants With EGFR Alterations or Fusions Recruiting USA 0


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