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Therapy Name CNTY-101
Synonyms
Therapy Description

CNTY-101 are iPSC-derived CAR-NK cells that have been engineered to express IL-15 and a chimeric antigen receptor (CAR) targeting CD19, which potentially results in tumor cell killing and inhibition of tumor growth (Blood (2021) 138 (Supplement 1): 1729).

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Drug Name Trade Name Synonyms Drug Classes Drug Description
CNTY-101 CNTY 101|CNTY101 CD19 Immune Cell Therapy 62 CNTY-101 are iPSC-derived CAR-NK cells that have been engineered to express IL-15 and a chimeric antigen receptor (CAR) targeting CD19, which potentially results in tumor cell killing and inhibition of tumor growth (Blood (2021) 138 (Supplement 1): 1729).

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT05336409 Phase I CNTY-101 A Study of CNTY-101 in Participants With CD19-Positive B-Cell Malignancies (ELiPSE-1) Recruiting USA 0


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