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Therapy Name	MB-106
Synonyms
Therapy Description	MB-106 are autologous T-lymphocytes engineered to express a chimeric antigen receptor (CAR) targeting CD20, and containing CD28 co-stimulatory and TNFRSF9 (4-1BB) and CD3zeta signaling domains, which potentially induce killing of tumor cells expressing CD20 (Blood (2021) 138 (Supplement 1): 3872; NCI Drug Dictionary).

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Drug Name	Trade Name	Synonyms	Drug Classes	Drug Description
MB-106		MB 106\|MB106	CD20 Immune Cell Therapy 13	MB-106 are autologous T-lymphocytes engineered to express a chimeric antigen receptor (CAR) targeting CD20, and containing CD28 co-stimulatory and TNFRSF9 (4-1BB) and CD3zeta signaling domains, which potentially induce killing of tumor cells expressing CD20 (Blood (2021) 138 (Supplement 1): 3872; NCI Drug Dictionary).

Filtering

Case insensitive filtering will display rows if any text in any cell matches the filter term
Use simple literal full or partial string matches
Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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Molecular Profile	Indication/Tumor Type	Response Type	Therapy Name	Approval Status	Evidence Type	Efficacy Evidence	References

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Case insensitive filtering will display rows if any text in any cell matches the filter term
Use simple literal full or partial string matches
Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
Click on any column header arrows to sort by that column
Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Clinical Trial	Phase	Therapies	Title	Recruitment Status	Covered Countries	Other Countries
NCT05360238	Phase Ib/II	MB-106	Study to Assess Safety, Tolerability and Efficacy of MB-106 in Patients With Relapsed or Refractory B-Cell NHL or CLL	Terminated	USA	0

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