Therapy Detail
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| Therapy Name | PRJ1-3024 |
| Synonyms | |
| Therapy Description |
PRJ1-3024 inhibits MAP4K1 (HPK1), which may reduce immunosuppression in the tumor microenvironment and result in induction of a cytotoxic T-lymphocyte (CTL) response against tumor cells (J Clin Oncol 42, 2024 (suppl 16; abstr 2590), NCI Drug Dictionary). |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| PRJ1-3024 | PRJ1 3024|PRJ13024 | MAP4K1 Inhibitor 8 | PRJ1-3024 inhibits MAP4K1 (HPK1), which may reduce immunosuppression in the tumor microenvironment and result in induction of a cytotoxic T-lymphocyte (CTL) response against tumor cells (J Clin Oncol 42, 2024 (suppl 16; abstr 2590), NCI Drug Dictionary). |
Filtering
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- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
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- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
- Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
Sorting
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- Click on any column header arrows to sort by that column
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| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT05159700 | Phase I | PRJ1-3024 | A Phase I Study, Evaluating the Safety, Pharmacokinetics and Efficacy of PRJ1-3024 in Subjects With Advanced Solid Tumors | Completed | USA | 0 |
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