Therapy Detail
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| Therapy Name | [212Pb]VMT01 |
| Synonyms | |
| Therapy Description |
[212Pb]VMT01 is a radioconjugate comprising the radionuclide 212Pb linked to a peptide targeting melanocortin 1 receptor (MC1R), which delivers radiation to MC1R-expressing tumor cells, potentially resulting in decreased tumor growth (PMID: 34359580). |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| [212Pb]VMT01 | VMT01 | [212Pb]VMT01 is a radioconjugate comprising the radionuclide 212Pb linked to a peptide targeting melanocortin 1 receptor (MC1R), which delivers radiation to MC1R-expressing tumor cells, potentially resulting in decreased tumor growth (PMID: 34359580). |
Filtering
- Case insensitive filtering will display rows if any text in any cell matches the filter term
- Use simple literal full or partial string matches
- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
- Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
Filtering
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- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
- Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
Sorting
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- Click on any column header arrows to sort by that column
- Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.
| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT05636618 | Phase Ib/II | [212Pb]VMT01 | Targeted Alpha-Particle Therapy for Advanced SSTR2 Positive Neuroendocrine Tumors ([212-Pb]-VMT) | Recruiting | USA | 0 |
| NCT05655312 | Phase Ib/II | [212Pb]VMT01 | MC1R-targeted Alpha-particle Therapy Trial in Adults With Advanced Melanoma | Recruiting | USA | 0 |
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