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Therapy Name [212Pb]VMT01
Synonyms
Therapy Description

[212Pb]VMT01 is a radioconjugate comprising the radionuclide 212Pb linked to a peptide targeting melanocortin 1 receptor (MC1R), which delivers radiation to MC1R-expressing tumor cells, potentially resulting in decreased tumor growth (PMID: 34359580).

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Drug Name Trade Name Synonyms Drug Classes Drug Description
[212Pb]VMT01 VMT01 [212Pb]VMT01 is a radioconjugate comprising the radionuclide 212Pb linked to a peptide targeting melanocortin 1 receptor (MC1R), which delivers radiation to MC1R-expressing tumor cells, potentially resulting in decreased tumor growth (PMID: 34359580).

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  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References

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  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT05636618 Phase Ib/II [212Pb]VMT01 Targeted Alpha-Particle Therapy for Advanced SSTR2 Positive Neuroendocrine Tumors ([212-Pb]-VMT) Recruiting USA 0
NCT05655312 Phase Ib/II [212Pb]VMT01 MC1R-targeted Alpha-particle Therapy Trial in Adults With Advanced Melanoma Recruiting USA 0


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