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Therapy Name AS-1763
Synonyms
Therapy Description

AS-1763 inhibits BTK, which potentially decreases tumor cell growth (PMID: 34529443).

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Drug Name Trade Name Synonyms Drug Classes Drug Description
AS-1763 AS 1763|AS1763|BN 102|BN-102|BN102|docirbrutinib BTK inhibitor 39 AS-1763 inhibits BTK, which potentially decreases tumor cell growth (PMID: 34529443).

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References
BTK C481S diffuse large B-cell lymphoma activated B-cell type sensitive AS-1763 Preclinical - Cell line xenograft Actionable In a preclinical study, AS-1763 inhibited proliferation of an activated B cell-like (ABC) diffuse large B-cell lymphoma cell line expressing BTK C481S in culture and inhibited tumor growth in a cell line xenograft model (PMID: 34529443). 34529443

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT05602363 Phase I AS-1763 AS-1763 in Patients With Previously Treated CLL/SLL or Non-Hodgkin Lymphoma Recruiting USA 0


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