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Therapy Detail
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| Therapy Name | BR101801 |
| Synonyms | |
| Therapy Description |
BR101801 inhibits PIK3CG, PIK3CD, and PRKDC (DNA-PK), which potentially leads to decreased proliferation and increased apoptosis of tumor cells and reduced tumor growth (PMID: 34873471, PMID: 36895970). |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| BR101801 | BR 101801|BR-101801 | DNA_PK Inhibitor 9 PIK3CD inhibitor 27 PIK3CG inhibitor 10 | BR101801 inhibits PIK3CG, PIK3CD, and PRKDC (DNA-PK), which potentially leads to decreased proliferation and increased apoptosis of tumor cells and reduced tumor growth (PMID: 34873471, PMID: 36895970). |
Filtering
- Case insensitive filtering will display rows if any text in any cell matches the filter term
- Use simple literal full or partial string matches
- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
- Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
Sorting
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- Click on any column header arrows to sort by that column
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
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- Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
Sorting
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- Click on any column header arrows to sort by that column
- Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.
| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT04018248 | Phase I | BR101801 | BR101801 in Adult Patients With Advanced Hematologic Malignancies( Phase I) | Active, not recruiting | USA | 1 |
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