Therapy Detail
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| Therapy Name | OT-A201 + Paclitaxel |
| Synonyms | |
| Therapy Description | |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| OT-A201 | OT A201|OTA201 | Limited information is currently available on OT-A201 (Jul 2023). | ||
| Paclitaxel | Taxol | 7-Epipaclitaxel | Antimicrotubule Agent 14 BCL2 Family Inhibitor 6 | Taxol (paclitaxel) binds to tubulin to inhibit microtubule disassembly, which results in decreased cell division, and also binds to the anti-apoptotic factor Bcl-2, promoting apoptosis (NCI Drug Dictionary). |
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
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- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
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| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT05828459 | Phase I | Lenalidomide + OT-A201 OT-A201 OT-A201 + Paclitaxel Bevacizumab + OT-A201 OT-A201 + Pomalidomide | First-in-human Study of OT-A201 in Patients With Selected Hematological Malignancies and Solid Tumors | Recruiting | FRA | 0 |
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