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Therapy Name AB-201
Synonyms
Therapy Description

AB-201 are cord-blood derived natural killer (NK) cells engineered to express a chimeric antigen receptor (CAR) that targets ERBB2 (HER2), which potentially results in tumor cell killing and growth inhibition in ERBB2 (HER2)-expressing tumors (Journal for ImmunoTherapy of Cancer 2021;9).

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Drug Name Trade Name Synonyms Drug Classes Drug Description
AB-201 AB 201|AB201 AB-201 are cord-blood derived natural killer (NK) cells engineered to express a chimeric antigen receptor (CAR) that targets ERBB2 (HER2), which potentially results in tumor cell killing and growth inhibition in ERBB2 (HER2)-expressing tumors (Journal for ImmunoTherapy of Cancer 2021;9).

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT05678205 Phase Ib/II AB-201 Cyclophosphamide + Fludarabine A Clinical Trial of the Safety and Anti-Tumor Activity of AB-201 in Subjects With Advanced HER2+ Solid Tumors Not yet recruiting USA 1
NCT06341647 Phase I Cyclophosphamide + Fludarabine AB-201 Phase 1 Clinical Trial to Evaluate the Safety and Anti-Tumor Activity of AB-201 Not yet recruiting AUS 0


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