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Therapy Name | E7 TCR T-cells |
Synonyms | |
Therapy Description |
E7 TCR T-cells are T-lymphocytes engineered to express a T-cell receptor targeting HPV16 E7, which potentially induce killing of HPV-positive tumor cells (PMID: 33558725). |
Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
---|---|---|---|---|
E7 TCR T-cells | HPV-16 E7 TCR expressing T-cells | E7 TCR T-cells are T-lymphocytes engineered to express a T-cell receptor targeting HPV16 E7, which potentially induce killing of HPV-positive tumor cells (PMID: 33558725). |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
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Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
---|---|---|---|---|---|---|
NCT05686226 | Phase II | E7 TCR T-cells | E7 TCR-T Cell Immunotherapy for Human Papillomavirus (HPV) Associated Cancers | Recruiting | USA | 0 |