Therapy Detail
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| Therapy Name | HB0045 |
| Synonyms | |
| Therapy Description |
HB0045 is a combination of two anti-CD73 monoclonal antibodies, HB0039 and HB0039, which potentially reduces immunosuppression, leading to enhanced antitumor immune response and inhibition of tumor growth (PMID: 39738003). |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| HB0045 | HB-0045|HB 0045 | CD73 Antibody 13 | HB0045 is a combination of two anti-CD73 monoclonal antibodies, HB0039 and HB0039, which potentially reduces immunosuppression, leading to enhanced antitumor immune response and inhibition of tumor growth (PMID: 39738003). |
Filtering
- Case insensitive filtering will display rows if any text in any cell matches the filter term
- Use simple literal full or partial string matches
- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
- Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
Sorting
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- Click on any column header arrows to sort by that column
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
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- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
- Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
Sorting
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- Click on any column header arrows to sort by that column
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| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT06056323 | Phase Ib/II | HB0045 | A Study of HB0045 Injection in Patients With Advanced Solid Tumors | Recruiting | USA | 0 |
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