Therapy Detail
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| Therapy Name | AVC-201 |
| Synonyms | |
| Therapy Description |
AVC-201 (Allo-RevCAR01-T-CD123) comprises an allogeneic chimeric antigen receptor (CAR) T-cell therapy containing a universal switchable CAR targeting CD123 (IL3RA), which potentially induces killing of tumor cells expressing CD123 (IL3RA) (Cancer Res (2023) 83 (7_Supplement): 4095). |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| AVC-201 | AVC 201|AVC201 | CD123 (IL3RA) Immune Cell Therapy 5 | AVC-201 (Allo-RevCAR01-T-CD123) comprises an allogeneic chimeric antigen receptor (CAR) T-cell therapy containing a universal switchable CAR targeting CD123 (IL3RA), which potentially induces killing of tumor cells expressing CD123 (IL3RA) (Cancer Res (2023) 83 (7_Supplement): 4095). |
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- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
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- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
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| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT05949125 | Phase I | Cyclophosphamide + Fludarabine AVC-201 | Phase 1 Study of Allo-RevCAR01-T-CD123 in Patients With Selected CD123 Positive Hematologic Malignancies (1b Dose Expansion) (RevSTAR-123) | Recruiting | NLD | DEU | 0 |
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