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Therapy Name AVC-201
Synonyms
Therapy Description

AVC-201 (Allo-RevCAR01-T-CD123) comprises an allogeneic chimeric antigen receptor (CAR) T-cell therapy containing a universal switchable CAR targeting CD123, which potentially induces killing of tumor cells expressing CD123 (Cancer Res (2023) 83 (7_Supplement): 4095).

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Drug Name Trade Name Synonyms Drug Classes Drug Description
AVC-201 AVC 201|AVC201 AVC-201 (Allo-RevCAR01-T-CD123) comprises an allogeneic chimeric antigen receptor (CAR) T-cell therapy containing a universal switchable CAR targeting CD123, which potentially induces killing of tumor cells expressing CD123 (Cancer Res (2023) 83 (7_Supplement): 4095).

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  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References

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  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
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Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT05949125 Phase I Cyclophosphamide + Fludarabine AVC-201 Dose-escalating Trial With Allo-RevCAR01-T Cells in Combination With CD123 Target Module (R-TM123) for Participants With Selected Hematologic Malignancies Positive for CD123 Recruiting NLD | DEU 0


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