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Therapy Name | LCB84 + unspecified PD-1 antibody |
Synonyms | |
Therapy Description | |
Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
---|---|---|---|---|
LCB84 | LCB 84|LCB-84 | TROP2 Antibody 14 | LCB84 is an antibody-drug conjugate (ADC) comprising an anti-TROP2 antibody linked to a monomethyl auristatin payload, with potential antitumor activity (Cancer Res (2022) 82 (12_Supplement): 328). | |
unspecified PD-1 antibody | Experimental PD-1 antibody | Immune Checkpoint Inhibitor 149 PD-L1/PD-1 antibody 122 |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
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Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
---|---|---|---|---|---|---|
NCT05941507 | Phase Ib/II | LCB84 + unspecified PD-1 antibody LCB84 | Phase 1/2 Study to Evaluate TROP2 ADC LCB84 Single Agent and in Combination With an Anti-PD-1 Ab in Advanced Solid Tumors | Recruiting | USA | CAN | 0 |