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Therapy Name CMV-CD19 CAR T-cells + Multi-antigen CMV-modified vaccinia Ankara vaccine
Synonyms
Therapy Description

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Drug Name Trade Name Synonyms Drug Classes Drug Description
CMV-CD19 CAR T-cells CD19 Immune Cell Therapy 64 CMV-CD19 CAR T-cells are CMV-specific T-cells that are engineered to express a chimeric antigen receptor (CAR) targeting CD19, which may stimulate an anti-tumor response against CD19-expressing tumors (PMID: 35027426, PMID: 25838392).
Multi-antigen CMV-modified vaccinia Ankara vaccine CMV-MVA Triplex Vaccine|CMV-Modified Vaccinia Ankara Vaccine Multi-antigen CMV-modified vaccinia Ankara vaccine is viral-based vaccine engineered to express three cytomegalovirus (CMV) antigens, which may induce a CMV-specific immune response (PMID: 27760761, PMID: 35272066).

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  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
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Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT06735690 Phase I CMV-CD19 CAR T-cells CMV-CD19 CAR T-cells + Multi-antigen CMV-modified vaccinia Ankara vaccine Allogeneic CMV-Specific CD19-CAR T Cells Plus CMV-MVA Triplex Vaccine After Matched Related Donor Hematopoietic Cell Transplant for the Treatment of Patients With High-Risk Acute Lymphoblastic Leukemia Not yet recruiting USA 0
NCT05801913 Phase I CMV-CD19 CAR T-cells + Multi-antigen CMV-modified vaccinia Ankara vaccine Genetically Modified T-cells (CMV-Specific CD19-CAR T-cells) Plus a Vaccine (CMV-MVA Triplex) for the Treatment of Intermediate or High Grade B-Cell Non-Hodgkin Lymphoma Recruiting USA 0


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