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Therapy Name | ONCT-808 |
Synonyms | |
Therapy Description |
ONCT-808 are autologous T-lymphocytes engineered to express a chimeric antigen receptor (CAR) that targets ROR1, potentially resulting in cytotoxicity against tumor cells expressing ROR1 (NCI Drug Dictionary). |
Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
---|---|---|---|---|
ONCT-808 | ONCT808|ONCT 808 | ONCT-808 are autologous T-lymphocytes engineered to express a chimeric antigen receptor (CAR) that targets ROR1, potentially resulting in cytotoxicity against tumor cells expressing ROR1 (NCI Drug Dictionary). |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
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Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
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NCT05588440 | Phase Ib/II | Cyclophosphamide + Fludarabine ONCT-808 | A Clinical Study of ONCT-808 in Subjects With Relapsed or Refractory B-Cell Malignancies | Terminated | USA | 0 |