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Therapy Name | TARA-002 |
Synonyms | |
Therapy Description |
TARA-002 consists of a lyophilized preparation of group A Streptococcus pyogenes treated with benzylpenicillin, which potentially enhances antitumor immune response (J Clin Oncol 41, 16_suppl TPS4618), NCI Drug Dictionary). |
Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
---|---|---|---|---|
TARA-002 | TARA002|TARA 002 | TARA-002 consists of a lyophilized preparation of group A Streptococcus pyogenes treated with benzylpenicillin, which potentially enhances antitumor immune response (J Clin Oncol 41, 16_suppl TPS4618), NCI Drug Dictionary). |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
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Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
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NCT05085990 | Phase I | TARA-002 | Safety and Toxicity Study of Intravesical Instillation of TARA-002 in Adults With High-grade Non-muscle Invasive Bladder Cancer (ADVANCED-1) | Completed | USA | 0 |
NCT05951179 | Phase Ib/II | TARA-002 | Dose Expansion, Safety and Efficacy Study of Intravesical Instillation of TARA-002 in Adults With High-grade Non-muscle Invasive Bladder Cancer (ADVANCED-2) | Recruiting | USA | CAN | 1 |
NCT05085977 | Phase I | TARA-002 | Safety and Toxicity Study of Intravesical Instillation of TARA-002 in Adults With High-grade Non-muscle Invasive Bladder Cancer (Phase 1a) (ADVANCED-1) | Active, not recruiting | USA | ROU | 2 |