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Therapy Detail

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Therapy Name TARA-002
Synonyms
Therapy Description

TARA-002 consists of a lyophilized preparation of group A Streptococcus pyogenes treated with benzylpenicillin, which potentially enhances antitumor immune response (J Clin Oncol 41, 16_suppl TPS4618), NCI Drug Dictionary).

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Drug Name Trade Name Synonyms Drug Classes Drug Description
TARA-002 TARA002|TARA 002 TARA-002 consists of a lyophilized preparation of group A Streptococcus pyogenes treated with benzylpenicillin, which potentially enhances antitumor immune response (J Clin Oncol 41, 16_suppl TPS4618), NCI Drug Dictionary).

Filtering

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  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References

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  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
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Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT05951179 Phase Ib/II TARA-002 Dose Expansion, Safety and Efficacy Study of Intravesical Instillation of TARA-002 in Adults With High-grade Non-muscle Invasive Bladder Cancer (ADVANCED-2) Recruiting USA | CAN | ARG 1
NCT05085990 Phase I TARA-002 Safety and Toxicity Study of Intravesical Instillation of TARA-002 in Adults With High-grade Non-muscle Invasive Bladder Cancer (ADVANCED-1) Completed USA 0
NCT05085977 Phase I TARA-002 Safety and Toxicity Study of Intravesical Instillation of TARA-002 in Adults With High-grade Non-muscle Invasive Bladder Cancer (Phase 1a) (ADVANCED-1) Completed USA | ROU 2


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