Therapy Detail
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| Therapy Name | BAY3546828 |
| Synonyms | |
| Therapy Description |
BAY3546828 comprises a monoclonal antibody that targets PSMA linked to the radionuclide Actinium-225, which potentially inhibits tumor growth (Cancer Res (2023) 83 (7_Supplement): 5047). |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| BAY3546828 | BAY 3546828|actinium-225-macropa-pelgifatamab|225Ac-pelgi|225Ac-pelgifatamab | PSMA Antibody 22 | BAY3546828 comprises a monoclonal antibody that targets PSMA linked to the radionuclide Actinium-225, which potentially inhibits tumor growth (Cancer Res (2023) 83 (7_Supplement): 5047). |
Filtering
- Case insensitive filtering will display rows if any text in any cell matches the filter term
- Use simple literal full or partial string matches
- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
- Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
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- Click on any column header arrows to sort by that column
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
Filtering
- Case insensitive filtering will display rows if any text in any cell matches the filter term
- Use simple literal full or partial string matches
- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
- Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
Sorting
- Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
- Click on any column header arrows to sort by that column
- Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.
| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT06052306 | Phase I | BAY3546828 | A Study to Learn How Safe the Study Treatment Actinium-225-macropa-pelgifatamab (BAY3546828) is, How it Affects the Body, How it Moves Into, Through and Out of the Body, and About Its Anticancer Activity in Participants With Advanced Metastatic Castration-resistant Prostate Cancer (mCRPC) | Recruiting | USA | SWE | NLD | ITA | GBR | FIN | CHE | CAN | 0 |
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