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Therapy Name INCA33890
Synonyms
Therapy Description

INCA33890 is a bispecific antibody targeting PDCD1 (PD-1) and TGFBR2, which potentially induces cytokine production and inhibits tumor growth (Cancer Res (2023) 83 (7_Supplement): 2936).

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Drug Name Trade Name Synonyms Drug Classes Drug Description
INCA33890 INCA-33890|INCA 33890 PD-L1/PD-1 antibody 132 TGFBR2 Antibody 3 INCA33890 is a bispecific antibody targeting PDCD1 (PD-1) and TGFBR2, which potentially induces cytokine production and inhibits tumor growth (Cancer Res (2023) 83 (7_Supplement): 2936).

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT05836324 Phase I Cetuximab + INCA33890 Bevacizumab + Fluorouracil + INCA33890 + Irinotecan + Leucovorin INCA33890 Bevacizumab + Fluorouracil + INCA33890 + Leucovorin + Oxaliplatin Bevacizumab + INCA33890 A Study to Evaluate the Safety of INCA33890 in Participants With Advanced or Metastatic Solid Tumors Recruiting USA | ITA | GBR | FRA | ESP | DNK | CHE 1


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