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Therapy Name | MT-8421 |
Synonyms | |
Therapy Description |
MT-8421 is an engineered toxin body that targets regulatory T-cells expressing high levels of CTLA-4, potentially resulting in decreases in regulatory T-cells in the tumor microenvironment and increased proliferation of CD8- and CD4-positive T-cells (Journal for ImmunoTherapy of Cancer (2022), 83 (Supplement 2): 817). |