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Therapy Name | ONM-501 |
Synonyms | |
Therapy Description |
ONM-501 is a STING agonist comprising 2',3'-cGAMP encapsulated in PC7A micelles, which potentially induces anti-tumor immune response and inhibits tumor growth (Cancer Res (2022) 82 (12_Supplement): 4234). |
Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
---|---|---|---|---|
ONM-501 | ONM 501|ONM501 | STING1 Agonist 19 | ONM-501 is a STING agonist comprising 2',3'-cGAMP encapsulated in PC7A micelles, which potentially induces anti-tumor immune response and inhibits tumor growth (Cancer Res (2022) 82 (12_Supplement): 4234). |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
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Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
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NCT06022029 | Phase I | ONM-501 Cemiplimab + ONM-501 | A Dose Escalation and Dose Expansion Study of Intratumoral ONM-501 Alone and in Combination With Cemiplimab in Patients With Advanced Solid Tumors and Lymphomas. (ON-5001) | Recruiting | USA | AUS | 0 |