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Therapy Detail
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| Therapy Name | REM-422 |
| Synonyms | |
| Therapy Description |
REM-422 is an mRNA degrader targeting MYB, which induces nonsense-mediated decay of the MYB transcript and decreased Myb protein levels, potentially inhibiting tumor growth (Blood (2023)142 (Supplement 1): 1425). |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| REM-422 | REM 422|REM422 | REM-422 is an mRNA degrader targeting MYB, which induces nonsense-mediated decay of the MYB transcript and decreased Myb protein levels, potentially inhibiting tumor growth (Blood (2023)142 (Supplement 1): 1425). |
Filtering
- Case insensitive filtering will display rows if any text in any cell matches the filter term
- Use simple literal full or partial string matches
- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
- Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
Sorting
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- Click on any column header arrows to sort by that column
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
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- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
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- Click on any column header arrows to sort by that column
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| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT06297941 | Phase I | REM-422 | Study of REM-422 in Patients With AML or Higher Risk MDS | Recruiting | USA | FRA | 0 |
| NCT06118086 | Phase I | REM-422 | Study of REM-422 in Patients With Recurrent or Metastatic Adenoid Cystic Carcinoma | Recruiting | USA | FRA | 0 |
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