Therapy Detail
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| Therapy Name | 225Ac-PSMA-R2 |
| Synonyms | |
| Therapy Description |
225Ac-PSMA-R2 is a radioconjugate comprising the PSMA-targeting ligand PSMA-R2 linked to the radionuclide actinium-225, which delivers alpha radiation to PSMA-expressing tumor cells, potentially inducing cell killing (NCI Drug Dictionary). |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| 225Ac-PSMA-R2 | 225AcPSMA-R2|Ac225-PSMA-R2|[225Ac]Ac-PSMA-R2 | PSMA Antibody 22 | 225Ac-PSMA-R2 is a radioconjugate comprising the PSMA-targeting ligand PSMA-R2 linked to the radionuclide actinium-225, which delivers alpha radiation to PSMA-expressing tumor cells, potentially inducing cell killing (NCI Drug Dictionary). |
Filtering
- Case insensitive filtering will display rows if any text in any cell matches the filter term
- Use simple literal full or partial string matches
- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
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- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
Sorting
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- Click on any column header arrows to sort by that column
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| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT05983198 | Phase Ib/II | 225Ac-PSMA-R2 | Phase I/II Study of [225Ac]Ac-PSMA-R2 in PSMA-positive Prostate Cancer, With/Without Prior 177Lu-PSMA RLT (SatisfACtion) | Recruiting | USA | FRA | CAN | AUS | 0 |
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