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Therapy Name | GD2-CART01 |
Synonyms | |
Therapy Description |
GD2-CART01 comprises T-lymphocytes engineered to express a chimeric antigen receptor (CAR) that targets GD2 and contains CD28 and TNFRSF9 (4-1BB) costimulatory domains, along with inducible Caspase-9, which potentially induces cytotoxicity against GD2-expressing tumor cells and inhibits tumor growth (PMID: 29872565) |