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Therapy Name | ADCLEC.syn1 |
Synonyms | |
Therapy Description |
ADCLEC.syn1 comprises T-lymphocytes engineered to express a chimeric antigen receptor (CAR) targeting ADGRE2 and a chimeric costimulatory receptor (CCR) targeting CLEC12A (CLL1), which potentially induce tumor cell killing (PMID: 37802054). |