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Therapy Name | SOT201 |
Synonyms | |
Therapy Description |
SOT201 comprises a monoclonal antibody against PDCD1 (PD-1) fused to an IL-15 mutein and the sushi domain from IL15RA, which activates IL-15 signaling, potentially resulting in expansion of T-lymphocytes and tumor growth inhibition (J Immunother Cancer 2023;11). |