Therapy Detail
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| Therapy Name | IBI133 |
| Synonyms | |
| Therapy Description |
IBI133 is an antibody-drug conjugate (ADC) comprising a monoclonal antibody targeting ERBB3 (HER3) linked to a DNA topoisomerase I inhibitor, which may induce apoptosis and inhibit proliferation of ERBB3 (HER3)-expressing tumor cells (NCI Drug Dictionary). |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| IBI133 | IBI-133|IBI 133 | IBI133 is an antibody-drug conjugate (ADC) comprising a monoclonal antibody targeting ERBB3 (HER3) linked to a DNA topoisomerase I inhibitor, which may induce apoptosis and inhibit proliferation of ERBB3 (HER3)-expressing tumor cells (NCI Drug Dictionary). |
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- Use simple literal full or partial string matches
- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
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- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
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- Click on any column header arrows to sort by that column
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| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT06170190 | Phase Ib/II | IBI133 | A Multicentre,Study of IBI133 in Subjects With Unresectable, Locally Advanced or Metastatic Solid Tumours | Completed | AUS | 0 |
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