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Therapy Name 212Pb-VMT-alpha-NET
Synonyms
Therapy Description

212Pb-VMT-alpha-NET is a radioconjugate comprising the radionuclide 212Pb linked to a SSTR2 peptide analogue peptide, which delivers radiation to SSTR2-expressing tumor cells, potentially resulting in decreased tumor growth (J Nucl Med June 2023, 64 (supplement 1) P772, NCI Drug Dictionary).

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Drug Name Trade Name Synonyms Drug Classes Drug Description
212Pb-VMT-alpha-NET [212Pb] VMT-a-NET 212Pb-VMT-alpha-NET is a radioconjugate comprising the radionuclide 212Pb linked to a SSTR2 peptide analogue peptide, which delivers radiation to SSTR2-expressing tumor cells, potentially resulting in decreased tumor growth (J Nucl Med June 2023, 64 (supplement 1) P772, NCI Drug Dictionary).

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  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References

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Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT06479811 Phase I 212Pb-VMT-alpha-NET [212Pb]VMT-Alpha-NET in Metastatic or Inoperable Somatostatin-Receptor Positive Gastrointestinal Neuroendocrine Tumors, Pheochromocytoma/Paragangliomas, Small Cell Lung, Renal Cell, and Head and Neck Cancers Not yet recruiting USA 0
NCT06148636 Phase I 212Pb-VMT-alpha-NET A Safety Study of 212Pb-VMT-alpha-NET in Patients With Neuroendocrine Tumors Active, not recruiting USA 0
NCT06427798 Phase Ib/II 212Pb-VMT-alpha-NET Somatostatin-Receptors (SSTR)-Agonist [212Pb]VMT-alpha-NET in Metastatic or Inoperable SSTR+ Gastrointestinal Neuroendocrine Tumor and Pheochromocytoma/Paraganglioma Previously Treated With Systemic Targeted Radioligand Therapy Not yet recruiting USA 0


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