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Therapy Name Obecabtagene autoleucel
Synonyms
Therapy Description

Aucatzyl (obecabtagene autoleucel) comprises autologous T-lymphocytes engineered to express a chimeric antigen receptor (CAR) targeting CD19, which potentially decreases tumor growth (J Clin Oncol 41, no. 16_suppl (June 01, 2023) 7000). Aucatzyl (obecabtagene autoleucel) is FDA-approved for use in adult patients with relapsed or refractory B-cell precursor acute lymphoblastic leukemia (FDA.gov).

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Drug Name Trade Name Synonyms Drug Classes Drug Description
Obecabtagene autoleucel Aucatzyl Obe-cel|AUTO1|AUTO-1|AUTO 1 CD19 Immune Cell Therapy 65 Aucatzyl (obecabtagene autoleucel) comprises autologous T-lymphocytes engineered to express a chimeric antigen receptor (CAR) targeting CD19, which potentially decreases tumor growth (J Clin Oncol 41, no. 16_suppl (June 01, 2023) 7000). Aucatzyl (obecabtagene autoleucel) is FDA-approved for use in adult patients with relapsed or refractory B-cell precursor acute lymphoblastic leukemia (FDA.gov).

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT06173518 Phase I Obecabtagene autoleucel A Study of CD19 Targeted CAR T Cell Therapy in Pediatric Patients With Relapsed or Refractory B Cell Acute Lymphoblastic Leukemia (B ALL) and Aggressive Mature B-cell Non-Hodgkin Lymphoma (B NHL) Recruiting USA | GBR | ESP 0


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